Phentermine
TabletsGenerally, it is recommended by the Food and Drug Administration (FDA) that phentermine should be used short-term (usually interpreted as 'up to 12 weeks'), while following nonpharmacological approaches to weight loss such as healthy dieting and exercise. However, recommendations limiting its use for short-term treatment may be controversial. One reason given behind limiting its use to 12 weeks is drug tolerance, whereby phentermine loses its appetite-suppressing effects after the body adjusts to the drug. On the contrary, it has been shown that phentermine did not lose effectiveness in a 36-week trial. Due to the risk of insomnia, it is generally recommended that the drug be taken either before breakfast or 1-2 hours after breakfast.
Contraindications and warnings
??? ?Patients with the following should not use Phentermine:
o?? ?An allergy to any ingredient in Phentermine or other sympathomimetics (eg, pseudoephedrine)
o?? ?Are also taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) in the last 14 days
o?? ?Have severe high blood pressure, an overactive thyroid, glaucoma, heart or blood vessel disease, or severe narrowing of the blood vessels
o?? ?Are in an agitated state, or have a history of substance abuse
??? ?Some medical conditions may interact with Phentermine, patients with the following should consult with their doctor before using phentermine: o?? ?Are also taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) in the last 14 days
o?? ?Have severe high blood pressure, an overactive thyroid, glaucoma, heart or blood vessel disease, or severe narrowing of the blood vessels
o?? ?Are in an agitated state, or have a history of substance abuse
o?? ?Are pregnant, planning to become pregnant, or are breast-feeding
o?? ?Are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
o?? ?Have allergies to medicines, foods, or other substances
o?? ?Have a brain or spinal cord disorder, hardening of the arteries, high blood pressure, diabetes, or high cholesterol or lipid levels
??? ?Some medicines may interact with Phentermine, such as the following: o?? ?Are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
o?? ?Have allergies to medicines, foods, or other substances
o?? ?Have a brain or spinal cord disorder, hardening of the arteries, high blood pressure, diabetes, or high cholesterol or lipid levels
o?? ?Dexfenfluramine, fenfluramine, furazolidone, or MAOIs (eg, phenelzine) because the risk of serious side effects, such as increasing headache, high blood pressure, slow heart rate, elevated temperature, or possibly fatal lung problems, may be increased
o?? ?Serotonin specific reuptake inhibitors (eg, fluoxetine) because the risk of their side effects may be increased by Phentermine
o?? ?Guanadrel or guanethidine because their effectiveness may be decreased by Phentermine
o?? ?Serotonin specific reuptake inhibitors (eg, fluoxetine) because the risk of their side effects may be increased by Phentermine
o?? ?Guanadrel or guanethidine because their effectiveness may be decreased by Phentermine